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Added: 11/4/2009
Natural Eggshell Membrane (NEM®) was found to be an effective and safe option for the treatment of pain and stiffness associated with knee osteoarthritis, according to a study published in the journal Clinical Rheumatology.
In their study, researchers reported: "Natural Eggshell Membrane (NEM®) is a new novel dietary supplement that contains naturally occurring glycosaminoglycans and proteins essential for maintaining healthy articular cartilage and the surrounding synovium."
A randomized, multi-center, double-blind, placebo-controlled clinical study was conducted to evaluate the efficacy and safety of NEM as a treatment for pain and stiffness associated with osteoarthritis of the knee.
According to the study, supplementation with 500 mg per day of NEM significantly reduced both joint pain and stiffness compared to placebo at 10, 30 and 60 days. The study randomly assigned 67 patients to receive either the 500 mg per day dose of NEM or placebo for eight weeks.
Supplementation with NEM produced an absolute rate of response that was statistically significant (up to 26.6%) versus placebo at all time points for both pain and stiffness. Rapid responses were seen for mean pain subscores and mean stiffness subscores occurring after only 10 days of supplementation. No serious adverse events were reported during the study and the treatment was reported to be well tolerated by study participants.
Researchers concluded: "Natural Eggshell Membrane (NEM) is an effective and safe option for the treatment of pain and stiffness associated with knee osteoarthritis. Supplementation with 500 mg taken once daily significantly reduced both joint pain and stiffness compared to placebo."
Clinical Rheumatology Published online ahead of print.
