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Interviewer: Well, let's talk about that supplement, Magtein. Right? Is
that how you pronounce that?
Dr. Guosong Liu: Magtein
Interviewer: What about that product is different than a magnesium
supplement that people can buy?
Dr. Liu: So I just touched upon this issue briefly before. So when almost
nine years ago when we were work magnesium, we never thought we are going
to actually even... I'm a professor. So we more think about science and we
say we can give any magnesium compound. But after we study the magnesium
compound, you know, let's say, magnesium core, magnesium citric on the
market and we found actually there's one thing which are disappointed and
that is their bioavailability period is really, really low and magnesium is
known to cause diarrhea if you take too much. So that was original purpose
of the use of magnesium.
So we said, "Well, actually, in this case we don't want to cause diarrhea
and so you cannot take too much." So then we have been working on what are
called bio [inaudible: 00:00:58], which means you get [inaudible: 00:00:59]
magnesium and whether magnesium can get into your body first. So we
actually carried on a study and we found the only magnesium compound have a
really, really poor bioavailability.
So then we said, "Okay. Let's design something." So then we designed this
new, it's called Magtein, and we found Magtein had about 50 percent
bioavailability for bringing magnesium into your body. Of course, the 50
percent is good, but not, you know, that much because you could argue and
say, "Wow, you know, this design, beta magnesium compound, but I could take
even more. Right?" So what a big deal?
So what really surprised us is that because we want to increase the brain
magnesium, so when we carry out that's lucky for us when we do the further
experiment and we experiment, we found, in terms of bring out the brain
magnesium, this compound almost seems to be almost like black and white.
The only compound we can't significantly increase the brain magnesium. This
is the only company. So that's different from other magnesium companies in
that way.
So when we get into human, same thing. If we take 420 milligram of ordinary
magnesium, you don't feel anything. This magnesium company, if you take
little too much, they say 400, you just going to feel headache because it's
huge what the magnesium can do to the brain. So we have to control the
dosage to be very low and even on low dose, [inaudible: 00:02:33] is
enough. So right now, if you compare the [inaudible: 00:02:36] we recommend
to people, we only recommend per pixel. It's only contain 75 milligram of
magnesium, which is almost tiny. It's enough for people to feel the...
feels a lot.
Interviewer: Can you talk about why that product works better or is more
efficient.
Dr. Liu: This is actually why we talk brain bioavailability, which means
when the magnesium get into your blood, okay, I need [inaudible: 00:03:09].
The brain, if magnesium is so important for your brain function, then brain
magnesium has to be regulated. Your brain magnesium actually can fluctuate
based on you eating food because you take the food, you're more magnesium
into your body and actually there is fluctuation of magnesium in your
blood. Okay?
Interviewer: Okay.
Dr. Liu: Brain doesn't need, doesn't want to be fluctuated. So the brain
magnesium is actually higher that blood magnesium in human or in animals.
So this higher magnesium is maintained by basically actively transporting
magnesium from blood into the brain. So that's found. Actively
transporting. You require energy and independent transfer. So that's why
it's very difficult to increase the magnesium. Blood magnesium it will take
more, brain there's actual transporting process.
So this Magtein I-Threonate, this is Magtein, in fact, I have to confess we
don't know the full mechanism. Why? They are bitter. Actually bring the
magnesium up. Help the magnesium transfer into the brain. So that increase
is why they call it bioavailability of magnesium. So that's what's unique
about this compound. From products point of view, not from science point of
view.
Information
Dr. Guosong Liu is an expert in cognition and memory. He's also the principle investigator behind a magnesium supplement called Magtein. He describes why the supplement might be a better way to get the amount your body needs.
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