Interviewer: We talked about Alzheimer's a little bit. You do a lot of
research into that. You're speaking this weekend, or this week, about that.
How much do we actually know about that disease?
Dr. Guosong Liu: Yeah, so the Alzheimer's disease is obviously one of the
biggest problem Asian society has to face and a long time ago we are less
worried about Alzheimer's disease because we are killed by infection
disease or heart attack or some other disease, cancer, . . .
Dr. Liu: . . . for example. Now with the advance of modern medicine, we
live longer, longer. We're getting older, older, eventually, we are going
to see the benefit. I don't know whether it's benefit of [inaudible:
00:00:37] medicines and we've got Alzheimer's disease.
So Alzheimer's disease, if you look, fundamentally, is the degeneration,
atrophy of the brain. So, if you look at the biology, fundamentally, you
just see actually the brain start to shrink. So that's a problem.
Now why bring [inaudible: 00:00:56]. There a lot of hypothesis and one of
the leading hypothesis in the field is there is a molecule called a beta,
which trigger the neural degeneration. So that is a major hypothesis and
now our study [inaudible: 00:01:15] design, not nutritional, through our
design to target the inhibitor and, unfortunately, so far we haven't seen
any real breakthrough on that.
So magnesium therapy is going to attack the problem differently. So we
don't focus on a beta. We focus on [inaudible: 00:01:34] if the Alzheimer's
disease is a degeneration of the brain. Now we have done the experiment to
show magnesium is a pro-generation compound.
Dr. Liu: So one is degeneration, the other one is pro-generation. So if we
actually gave Alzheimer's disease more to mice or human, there's a pro-
generation, if we can prevent the degeneration, maybe we can solve the
problem, too. So that is a very simple idea, come really that simple.
So, so far we have done the animal study and the animal, if we put this
magnesium in in the high A beta background mice, which do have very fast
brain degeneration and loss [inaudible: 00:02:25] quickly. In those mortal
mice and we gave this compound and we can prevent degeneration.
Dr. Liu: So that's the... it's that simple. So they now will give to human
and we hope to at least stop degeneration. Right? So we could also give to
a human earlier and a prevention compound and the people who have a chance
to get Alzheimer's disease might need to take this a little bit earlier
than other. Or just eat some, you know, green vegetable . . .
Dr. Liu: . . . which contain all nuts which contain a lot of magnesium.
Right? Either you take the supplement or just take the food which have a
lot of magnesium.
Dr. Liu: So the idea itself is very straightforward and simple.